At 24 hours the plasma amounts of sildenafil have been still about 200 ng/mL, compared to somewhere around 5 ng/mL when sildenafil was dosed by itself. That is in step with ritonavir's marked effects with a wide range of P450 substrates. VIAGRA experienced no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS]
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